Assay Detail
Binding
CHEMBL2045474
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of porcine brain CK1delta/epsilon using CKS peptide as substrate
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of analogs of the marine alkaloids granulatimide and isogranulatimide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.80 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2041917 | — | — | 1 | 6.80 |
| CHEMBL2041919 | — | — | 1 | 6.64 |
| CHEMBL239698 | — | — | 1 | 5.96 |
| CHEMBL2041918 | — | — | 1 | 5.58 |
| CHEMBL2041914 | — | — | 1 | 5.50 |
| CHEMBL2041915 | — | — | 1 | 5.15 |
| CHEMBL393545 | — | — | 1 | 5.00 |
| CHEMBL2041749 | — | — | 1 | - |
| CHEMBL2041912 | — | — | 1 | - |
| CHEMBL2041916 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2041917 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL2041919 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL239698 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL2041918 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL2041914 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL2041915 | — | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL393545 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL2041749 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2041912 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2041916 | — | IC50 | > | 10000.0 | nM | - |