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Assay Detail

CHEMBL2045839

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human iNOS
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Nitric oxide synthase, inducible (CHEMBL4481)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

New synthesis and promising neuroprotective role in experimental ischemic stroke of ONO-1714.
Pozo-Rodrigálvarez A, Gradillas A, Serrano J, Fernández AP, Martínez-Murillo R, Pérez-Castells J.
Eur J Med Chem (2012) 54 : 439 -446
PubMed 22703704 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.74 8.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1800346 1 8.74

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1800346 Ki = 1.8 nM 8.74