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Assay Detail

CHEMBL2065343

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Binding
Inhibition of KIT
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Mast/stem cell growth factor receptor Kit (CHEMBL1936)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeted kinase selectivity from kinase profiling data.
Milletti F, Hermann JC.
ACS Med Chem Lett (2012) 3 : 383 -386
PubMed 24900482 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.70 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2062935 1 8.00
CHEMBL2022856 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2062935 Ki = 10.0 nM 8.00
CHEMBL2022856 Ki = 39.81 nM 7.40