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Assay Detail

CHEMBL2065345

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Binding
Inhibition of CDC7
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cell division cycle 7-related protein kinase (CHEMBL5443)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeted kinase selectivity from kinase profiling data.
Milletti F, Hermann JC.
ACS Med Chem Lett (2012) 3 : 383 -386
PubMed 24900482 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 9.43 9.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2062936 1 9.80
CHEMBL2062937 1 9.50
CHEMBL1999931 1 9.30
CHEMBL1983595 1 9.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2062936 Ki = 0.1585 nM 9.80
CHEMBL2062937 Ki = 0.3162 nM 9.50
CHEMBL1999931 Ki = 0.5012 nM 9.30
CHEMBL1983595 Ki = 0.7943 nM 9.10