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Assay Detail

CHEMBL2065348

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Binding
Inhibition of EGFR
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Epidermal growth factor receptor (CHEMBL203)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeted kinase selectivity from kinase profiling data.
Milletti F, Hermann JC.
ACS Med Chem Lett (2012) 3 : 383 -386
PubMed 24900482 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 7.10 7.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1090356 1 7.50
CHEMBL306380 1 6.70
CHEMBL2062938 1 -
CHEMBL406845 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1090356 Ki = 31.62 nM 7.50
CHEMBL306380 Ki = 199.53 nM 6.70
CHEMBL2062938 Ki > 10000.0 nM -
CHEMBL406845 Ki > 10000.0 nM -