Assay Detail
Binding
CHEMBL2065349
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CSF1R
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Macrophage colony-stimulating factor 1 receptor (CHEMBL1844) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeted kinase selectivity from kinase profiling data.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.40 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1970317 | — | — | 1 | 8.70 |
| CHEMBL2022856 | — | — | 1 | 8.50 |
| CHEMBL1980297 | ILORASERTIB | 2.0 | 1 | 8.50 |
| CHEMBL1964441 | — | — | 1 | 8.30 |
| CHEMBL1967720 | — | — | 1 | 8.30 |
| CHEMBL1979577 | — | — | 1 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1970317 | — | Ki | = | 1.995 | nM | 8.70 |
| CHEMBL2022856 | — | Ki | = | 3.162 | nM | 8.50 |
| CHEMBL1980297 | ILORASERTIB | Ki | = | 3.162 | nM | 8.50 |
| CHEMBL1964441 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL1967720 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL1979577 | — | Ki | = | 7.943 | nM | 8.10 |