Assay Detail
Binding
CHEMBL2065350
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Inhibition of PDGFRA
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Platelet-derived growth factor receptor alpha (CHEMBL2007) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeted kinase selectivity from kinase profiling data.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.33 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1980297 | ILORASERTIB | 2.0 | 1 | 9.10 |
| CHEMBL1964441 | — | — | 1 | 8.60 |
| CHEMBL1970317 | — | — | 1 | 7.30 |
| CHEMBL2022856 | — | — | 1 | - |
| CHEMBL1979577 | — | — | 1 | - |
| CHEMBL1967720 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1980297 | ILORASERTIB | Ki | = | 0.7943 | nM | 9.10 |
| CHEMBL1964441 | — | Ki | = | 2.512 | nM | 8.60 |
| CHEMBL1970317 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL2022856 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1979577 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1967720 | — | Ki | > | 10000.0 | nM | - |