Assay Detail
Binding
CHEMBL2072929
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to PPARgamma
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8739 | LINOLENIC ACID | — | 1 | 5.70 |
| CHEMBL482477 | — | — | 1 | 5.70 |
| CHEMBL2069934 | — | — | 1 | 5.70 |
| CHEMBL1077284 | — | — | 1 | 5.70 |
| CHEMBL460026 | ICOSAPENT | 3.0 | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8739 | LINOLENIC ACID | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL482477 | — | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL2069934 | — | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL1077284 | — | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL460026 | ICOSAPENT | Kd | = | 2000.0 | nM | 5.70 |