Assay Detail
Binding
CHEMBL2072949
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human EGFR using poly glu-Tyr as substrate after 30 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.23 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2070045 | — | — | 1 | 6.29 |
| CHEMBL2070048 | — | — | 1 | 6.16 |
| CHEMBL2070047 | — | — | 1 | - |
| CHEMBL2070050 | — | — | 1 | - |
| CHEMBL2070051 | — | — | 1 | - |
| CHEMBL2070075 | — | — | 1 | - |
| CHEMBL2070081 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2070045 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL2070048 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL2070047 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2070050 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2070051 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2070075 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2070081 | — | IC50 | > | 10000.0 | nM | - |