Assay Detail
Functional
CHEMBL2075310
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of BSP uptake in Xenopus laevis oocytes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Xenopus laevis |
| Cell Type | Oocyte |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Solute carrier organic anion transporter family member 1B3 (CHEMBL1743121) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.41 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL437765 | RIFAMYCIN | 4.0 | 1 | 5.52 |
| CHEMBL374478 | RIFAMPIN | 4.0 | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL437765 | RIFAMYCIN | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL374478 | RIFAMPIN | Ki | = | 5000.0 | nM | 5.30 |