Solute carrier organic anion transporter family member 1B3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9NPD5. Use UniProt Q9NPD5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NPD5 as the stable identity anchor, then attach disease evidence before program review.
Solute carrier organic anion transporter family member 1B3
Review this target as Solute carrier organic anion transporter family member 1B3, mapped to UniProt Q9NPD5. Sequence length is 702 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Solute carrier organic anion transporter family member 1B3 as ChEMBL target CHEMBL1743121, mapped to UniProt Q9NPD5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Solute carrier organic anion transporter family member 1B3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9NPD5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Solute carrier organic anion transporter family member 1B3 |
| UniProt Accession | Q9NPD5 |
| Component Type | Protein |
| Sequence Length | 702 aa |
Solute carrier organic anion transporter family member 1B3
Review this target as Solute carrier organic anion transporter family member 1B3, mapped to UniProt Q9NPD5. Sequence length is 702 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4636474 | 8.85 | EC50 | 1.4 | Preclinical |
| CHEMBL4637446 | 8.62 | EC50 | 2.4 | Preclinical |
| CHEMBL4633668 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL1171146 | 7.1 | Ki | 80.0 | Preclinical |
| CHEMBL1171146 | 6.98 | IC50 | 104.71 | Preclinical |
| CHEMBL160 | 6.89 | IC50 | 130.0 | Approved |
| CHEMBL3704745 | 6.72 | IC50 | 190.0 | Preclinical |
| CHEMBL1651956 | 6.66 | IC50 | 220.0 | Clinical |
| CHEMBL428647 | 6.58 | IC50 | 260.0 | Approved |
| CHEMBL1163 | 6.43 | Ki | 370.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 61 | 96 | 5.6 |
| single protein format | 14 | 11 | 5.1 |
| assay format | 4 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 27 | 3 | 5.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 14 | 2 | 4.8 |
| cell-based format | 10 | 5 | 6.5 |