Assay Detail
Functional
CHEMBL2075864
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HEK293 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Solute carrier family 22 member 3 (CHEMBL2073673) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.37 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL339858 | DISPROCYNIUM24 | — | 1 | 7.82 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL339858 | DISPROCYNIUM24 | Ki | = | 15.0 | nM | 7.82 |
| CHEMBL107 | COLCHICINE | Ki | = | 120.0 | nM | 6.92 |