Assay Detail
Functional
CHEMBL2076375
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of LTC4 uptake in membrane vesicle from MRP1-expressing HeLa cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | HeLa |
| Subcellular | Membrane vesicle |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Multidrug resistance-associated protein 1 (CHEMBL3004) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.39 | 6.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1628111 | — | — | 1 | 6.42 |
| CHEMBL494753 | ESTRONE SULFURIC ACID | 4.0 | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1628111 | — | Ki | = | 380.0 | nM | 6.42 |
| CHEMBL494753 | ESTRONE SULFURIC ACID | Ki | = | 450.0 | nM | 6.35 |