Assay Detail
Functional
CHEMBL2077091
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TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT3-expressing S2 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | S2 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Characterization of ochratoxin A transport by human organic anion transporters.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.05 | 5.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL897 | PROBENECID | 4.0 | 1 | 5.36 |
| CHEMBL527 | PIROXICAM | 4.0 | 1 | 5.31 |
| CHEMBL324846 | OCTANOIC ACID | 2.0 | 1 | 5.07 |
| CHEMBL510139 | CITRININ | — | 1 | 4.81 |
| CHEMBL463 | AMINOHIPPURIC ACID | 4.0 | 1 | 4.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL897 | PROBENECID | Ki | = | 4410.0 | nM | 5.36 |
| CHEMBL527 | PIROXICAM | Ki | = | 4880.0 | nM | 5.31 |
| CHEMBL324846 | OCTANOIC ACID | Ki | = | 8600.0 | nM | 5.07 |
| CHEMBL510139 | CITRININ | Ki | = | 15400.0 | nM | 4.81 |
| CHEMBL463 | AMINOHIPPURIC ACID | Ki | = | 19600.0 | nM | 4.71 |