Assay Detail
Functional
CHEMBL2089594
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at beta2-adrenoceptor in human bronchial smooth-muscle cell by cAMP assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
An investigation into the structure-activity relationships associated with the systematic modification of the β(2)-adrenoceptor agonist indacaterol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.12 | 9.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2088201 | — | — | 1 | 9.55 |
| CHEMBL1346 | DARIFENACIN | 4.0 | 1 | 8.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2088201 | — | EC50 | = | 0.28 | nM | 9.55 |
| CHEMBL1346 | DARIFENACIN | EC50 | = | 2.05 | nM | 8.69 |