Beta-2 adrenergic receptor · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Beta-2 adrenergic receptor shows approved-linked disease relevance led by chronic obstructive pulmonary disease. 5 more disease programs remain visible in the same review block. 21 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P07550. Start with chronic obstructive pulmonary disease, then reuse UniProt P07550 as the stable protein anchor across project notes and exports.
Start with chronic obstructive pulmonary disease, then reuse UniProt P07550 as the stable protein anchor across project notes and exports.
Beta-2 adrenergic receptor shows approved-linked disease relevance led by chronic obstructive pulmonary disease. 5 more disease programs remain visible in the same review block. 21 linked drugs remain visible in the same block.
Start review with chronic obstructive pulmonary disease because it currently carries approved-linked support. Linked drugs include ABEDITEROL, ALBUTEROL, ALBUTEROL SULFATE, ARFORMOTEROL TARTRATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyBeta-2 adrenergic receptor
Review this target as Beta-2 adrenergic receptor, mapped to UniProt P07550. Sequence length is 413 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-2 adrenergic receptor as ChEMBL target CHEMBL210, mapped to UniProt P07550. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Beta-2 adrenergic receptor is the right protein anchor across sources, using UniProt P07550 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why chronic obstructive pulmonary disease is currently framed as approved-linked support. It currently carries 21 linked drugs in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Beta-2 adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P07550 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-2 adrenergic receptor |
| UniProt Accession | P07550 |
| Component Type | Protein |
| Sequence Length | 413 aa |
Beta-2 adrenergic receptor
Review this target as Beta-2 adrenergic receptor, mapped to UniProt P07550. Sequence length is 413 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Beta-2 adrenergic receptor shows approved-linked disease relevance led by chronic obstructive pulmonary disease. 5 more disease programs remain visible in the same review block.
Start review with chronic obstructive pulmonary disease because it currently carries approved-linked support. Linked drugs include ABEDITEROL, ALBUTEROL, ALBUTEROL SULFATE, ARFORMOTEROL TARTRATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4847536 | 10.97 | EC50 | 0.01072 | Preclinical |
| CHEMBL5570917 | 10.94 | EC50 | 0.01148 | Preclinical |
| CHEMBL2012522 | 10.92 | Ki | 0.012 | Preclinical |
| CHEMBL4871708 | 10.9 | EC50 | 0.01259 | Preclinical |
| CHEMBL6067690 | 10.9 | Ki | 0.01259 | Preclinical |
| CHEMBL5550055 | 10.9 | Ki | 0.01259 | Preclinical |
| CHEMBL5517637 | 10.9 | Ki | 0.01259 | Preclinical |
| CHEMBL4871517 | 10.9 | Ki | 0.01259 | Preclinical |
| CHEMBL4873082 | 10.89 | EC50 | 0.01288 | Preclinical |
| CHEMBL5571865 | 10.88 | EC50 | 0.01318 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 323 | 349 | 7.7 |
| cell-based format | 163 | 797 | 6.5 |
| assay format | 19 | 185 | 8.1 |
| cell membrane format | 9 | 73 | 7.1 |
| organism-based format | 1 | 1 | 6.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 247 | 1,021 | 8.2 |
| assay format | 84 | 231 | 6.5 |
| single protein format | 6 | 28 | 7.4 |
| cell membrane format | 1 | 13 | 7.4 |
| tissue-based format | 1 | 1 | 8.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 0 | — |
| cell-based format | 3 | 1 | 7.9 |