Assay Detail
Functional
CHEMBL2090728
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against liver stages of Plasmodium yoelii yoelii
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium yoelii yoelii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting the liver stage of malaria parasites: a yet unmet goal.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.58 | 9.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL593 | DELAVIRDINE | 4.0 | 1 | 9.07 |
| CHEMBL45816 | MIBEFRADIL | 4.0 | 1 | 9.06 |
| CHEMBL139702 | LICOAGROCHACONE A | — | 1 | 9.03 |
| CHEMBL926 | DOBUTAMINE | 4.0 | 1 | 8.43 |
| CHEMBL959 | RIMANTADINE | 4.0 | 1 | 7.45 |
| CHEMBL506 | PRIMAQUINE | 4.0 | 1 | 7.12 |
| CHEMBL207990 | EPOXOMYCIN | — | 1 | 5.40 |
| CHEMBL159 | VINBLASTINE | 4.0 | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL593 | DELAVIRDINE | IC50 | = | 0.846 | nM | 9.07 |
| CHEMBL45816 | MIBEFRADIL | IC50 | = | 0.873 | nM | 9.06 |
| CHEMBL139702 | LICOAGROCHACONE A | IC50 | = | 0.927 | nM | 9.03 |
| CHEMBL926 | DOBUTAMINE | IC50 | = | 3.7 | nM | 8.43 |
| CHEMBL959 | RIMANTADINE | IC50 | = | 35.6 | nM | 7.45 |
| CHEMBL506 | PRIMAQUINE | IC50 | = | 75.7 | nM | 7.12 |
| CHEMBL207990 | EPOXOMYCIN | IC50 | = | 3950.0 | nM | 5.40 |
| CHEMBL159 | VINBLASTINE | IC50 | = | 7950.0 | nM | 5.10 |