Assay Detail
Functional
CHEMBL2090752
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against liver stages of Plasmodium yoelii after 96 hrs
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium yoelii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting the liver stage of malaria parasites: a yet unmet goal.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.85 | 5.00 |
| INH | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11301 | DESFERRITHIOCIN | — | 1 | 5.00 |
| CHEMBL556 | DEFEROXAMINE | 4.0 | 1 | 4.70 |
| CHEMBL1738 | DEXRAZOXANE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11301 | DESFERRITHIOCIN | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL556 | DEFEROXAMINE | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL1738 | DEXRAZOXANE | INH | = | 50.0 | uM | - |