Assay Detail
Functional
CHEMBL2114719
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PubChem BioAssay. Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2. (Class of assay: confirmatory)
365
Total Activities
364
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | confirmatory |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 365 | 4.48 | 5.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1428659 | — | — | 1 | 5.84 |
| CHEMBL1408099 | — | — | 1 | 5.75 |
| CHEMBL1466102 | — | — | 1 | 5.66 |
| CHEMBL1407390 | — | — | 1 | 5.59 |
| CHEMBL1995078 | — | — | 1 | 5.56 |
| CHEMBL1608954 | — | — | 1 | 5.56 |
| CHEMBL1560655 | — | — | 1 | 5.55 |
| CHEMBL1311572 | — | — | 1 | 5.54 |
| CHEMBL1866688 | — | — | 1 | 5.45 |
| CHEMBL502315 | — | — | 1 | 5.42 |
| CHEMBL1530862 | — | — | 1 | 5.32 |
| CHEMBL1344582 | — | — | 1 | 5.30 |
| CHEMBL1390388 | — | — | 1 | 5.29 |
| CHEMBL1403349 | — | — | 1 | 5.23 |
| CHEMBL1347974 | — | — | 1 | 5.19 |
| CHEMBL1308898 | — | — | 1 | 5.18 |
| CHEMBL1467579 | — | — | 1 | 5.17 |
| CHEMBL1491651 | — | — | 1 | 5.15 |
| CHEMBL1604614 | — | — | 1 | 5.13 |
| CHEMBL1519452 | — | — | 1 | 5.13 |
| CHEMBL1880991 | — | — | 1 | 5.06 |
| CHEMBL1325071 | — | — | 1 | 5.05 |
| CHEMBL1899739 | — | — | 1 | 5.05 |
| CHEMBL1505809 | — | — | 1 | 5.04 |
| CHEMBL1335915 | — | — | 1 | 5.04 |
| CHEMBL1608480 | — | — | 1 | 5.03 |
| CHEMBL1522206 | — | — | 1 | 4.99 |
| CHEMBL1727324 | — | — | 1 | 4.99 |
| CHEMBL1711260 | — | — | 1 | 4.98 |
| CHEMBL1364058 | — | — | 1 | 4.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1428659 | — | IC50 | = | 1460.0 | nM | 5.84 |
| CHEMBL1408099 | — | IC50 | = | 1790.0 | nM | 5.75 |
| CHEMBL1466102 | — | IC50 | = | 2190.0 | nM | 5.66 |
| CHEMBL1407390 | — | IC50 | = | 2540.0 | nM | 5.59 |
| CHEMBL1995078 | — | IC50 | = | 2780.0 | nM | 5.56 |
| CHEMBL1608954 | — | IC50 | = | 2730.0 | nM | 5.56 |
| CHEMBL1560655 | — | IC50 | = | 2810.0 | nM | 5.55 |
| CHEMBL1311572 | — | IC50 | = | 2850.0 | nM | 5.54 |
| CHEMBL1866688 | — | IC50 | = | 3570.0 | nM | 5.45 |
| CHEMBL502315 | — | IC50 | = | 3840.0 | nM | 5.42 |
| CHEMBL1530862 | — | IC50 | = | 4790.0 | nM | 5.32 |
| CHEMBL1344582 | — | IC50 | = | 5040.0 | nM | 5.30 |
| CHEMBL1390388 | — | IC50 | = | 5090.0 | nM | 5.29 |
| CHEMBL1403349 | — | IC50 | = | 5860.0 | nM | 5.23 |
| CHEMBL1347974 | — | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL1308898 | — | IC50 | = | 6630.0 | nM | 5.18 |
| CHEMBL1467579 | — | IC50 | = | 6820.0 | nM | 5.17 |
| CHEMBL1491651 | — | IC50 | = | 7010.0 | nM | 5.15 |
| CHEMBL1519452 | — | IC50 | = | 7450.0 | nM | 5.13 |
| CHEMBL1604614 | — | IC50 | = | 7320.0 | nM | 5.13 |
| CHEMBL1880991 | — | IC50 | = | 8620.0 | nM | 5.06 |
| CHEMBL1325071 | — | IC50 | = | 8820.0 | nM | 5.05 |
| CHEMBL1899739 | — | IC50 | = | 8890.0 | nM | 5.05 |
| CHEMBL1505809 | — | IC50 | = | 9100.0 | nM | 5.04 |
| CHEMBL1335915 | — | IC50 | = | 9100.0 | nM | 5.04 |
| CHEMBL1608480 | — | IC50 | = | 9310.0 | nM | 5.03 |
| CHEMBL1727324 | — | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL1522206 | — | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL1711260 | — | IC50 | = | 10400.0 | nM | 4.98 |
| CHEMBL1364058 | — | IC50 | = | 10800.0 | nM | 4.97 |
| CHEMBL1532349 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL1409219 | — | IC50 | = | 10900.0 | nM | 4.96 |
| CHEMBL1477304 | — | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL1503172 | — | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL1373822 | — | IC50 | = | 11500.0 | nM | 4.94 |
| CHEMBL1575487 | — | IC50 | = | 11800.0 | nM | 4.93 |
| CHEMBL1390833 | — | IC50 | = | 11900.0 | nM | 4.92 |
| CHEMBL1564386 | — | IC50 | = | 11900.0 | nM | 4.92 |
| CHEMBL1706710 | — | IC50 | = | 11900.0 | nM | 4.92 |
| CHEMBL1323785 | — | IC50 | = | 12200.0 | nM | 4.91 |
| CHEMBL1573529 | — | IC50 | = | 12200.0 | nM | 4.91 |
| CHEMBL191015 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL1416100 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL1440055 | — | IC50 | = | 12700.0 | nM | 4.90 |
| CHEMBL1698134 | — | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL1469808 | — | IC50 | = | 12800.0 | nM | 4.89 |
| CHEMBL1526471 | — | IC50 | = | 13200.0 | nM | 4.88 |
| CHEMBL1424434 | — | IC50 | = | 13700.0 | nM | 4.86 |
| CHEMBL1598347 | — | IC50 | = | 13800.0 | nM | 4.86 |
| CHEMBL1610263 | — | IC50 | = | 14200.0 | nM | 4.85 |