Assay Detail
Binding
CHEMBL2154568
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]CPX from adenosine A1 receptor in rat brain cortical membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.96 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2153721 | — | — | 1 | 9.52 |
| CHEMBL418101 | — | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2153721 | — | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL418101 | — | Ki | = | 4.0 | nM | 8.40 |