Assay Detail
Binding
CHEMBL2155052
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-DPDPE from mouse DOR expressed in HEK293 cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tuned-Affinity Bivalent Ligands for the Characterization of Opioid Receptor Heteromers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 7.12 | 8.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1237164 | NALTRINDOLE HYDROCHLORIDE | — | 1 | 8.58 |
| CHEMBL13470 | SNC-80 | — | 1 | 7.78 |
| CHEMBL2151245 | — | — | 1 | 7.70 |
| CHEMBL2151247 | — | — | 1 | 7.51 |
| CHEMBL2151328 | — | — | 1 | 7.04 |
| CHEMBL2151327 | — | — | 1 | 6.69 |
| CHEMBL963 | OXYMORPHONE | 4.0 | 1 | 6.14 |
| CHEMBL2151246 | — | — | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1237164 | NALTRINDOLE HYDROCHLORIDE | Ki | = | 2.63 | nM | 8.58 |
| CHEMBL13470 | SNC-80 | Ki | = | 16.6 | nM | 7.78 |
| CHEMBL2151245 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL2151247 | — | Ki | = | 30.9 | nM | 7.51 |
| CHEMBL2151328 | — | Ki | = | 91.2 | nM | 7.04 |
| CHEMBL2151327 | — | Ki | = | 204.17 | nM | 6.69 |
| CHEMBL963 | OXYMORPHONE | Ki | = | 724.44 | nM | 6.14 |
| CHEMBL2151246 | — | Ki | = | 2884.03 | nM | 5.54 |