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Assay Detail

CHEMBL2155625

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAchR in mouse hippocampal membranes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Tissue Hippocampus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Neuronal acetylcholine receptor subunit alpha-7 (CHEMBL3365)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Discovery and development of α7 nicotinic acetylcholine receptor modulators.
Mazurov AA, Speake JD, Yohannes D.
J Med Chem (2011) 54 : 7943 -7961
PubMed 21919481 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.15 8.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2151573 1 8.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2151573 Ki = 7.04 nM 8.15