Assay Detail
Binding
CHEMBL2155980
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human ACE C-terminal domain expressed in CHO cells after 90 mins by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Remarkable potential of the α-aminophosphonate/phosphinate structural motif in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.61 | 9.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL570953 | — | — | 1 | 9.19 |
| CHEMBL2153740 | — | — | 1 | 8.52 |
| CHEMBL1235767 | — | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL570953 | — | Ki | = | 0.65 | nM | 9.19 |
| CHEMBL2153740 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL1235767 | — | Ki | = | 7500.0 | nM | 5.12 |