Assay Detail
Binding
CHEMBL2156898
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EGFR
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase γ inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.26 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2152253 | — | — | 1 | 6.39 |
| CHEMBL2152252 | — | — | 1 | 6.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2152253 | — | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL2152252 | — | IC50 | = | 739.0 | nM | 6.13 |