Assay Detail
Binding
CHEMBL2162909
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Inhibition of human factor 10a assessed as CBS 31.39 substrate hydrolysis by spectrophotometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Polysulfated xanthones: multipathway development of a new generation of dual anticoagulant/antiplatelet agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.34 | 8.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL198362 | RIVAROXABAN | 4.0 | 1 | 8.34 |
| CHEMBL2158201 | MANGIFERIN HEPTASULFATE | — | 1 | - |
| CHEMBL2158198 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL198362 | RIVAROXABAN | IC50 | = | 4.59 | nM | 8.34 |
| CHEMBL2158201 | MANGIFERIN HEPTASULFATE | IC50 | = | 970000.0 | nM | - |
| CHEMBL2158198 | — | IC50 | = | 740000.0 | nM | - |