Assay Detail
Binding
CHEMBL2163147
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human LMW-PTPase isoform 1
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Low molecular weight phosphotyrosine protein phosphatase (CHEMBL4903) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Low molecular weight phosphotyrosine protein phosphatases as emerging targets for the design of novel therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.77 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1765349 | — | — | 1 | 6.30 |
| CHEMBL2158214 | — | — | 1 | 5.24 |
| CHEMBL2158217 | — | — | 1 | - |
| CHEMBL2158216 | — | — | 1 | - |
| CHEMBL2158219 | — | — | 1 | - |
| CHEMBL2158218 | — | — | 1 | - |
| CHEMBL2158220 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1765349 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL2158214 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL2158217 | — | IC50 | = | 5300000.0 | nM | - |
| CHEMBL2158216 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL2158219 | — | IC50 | = | 300000.0 | nM | - |
| CHEMBL2158218 | — | IC50 | = | 14000000.0 | nM | - |
| CHEMBL2158220 | — | IC50 | = | 1790000.0 | nM | - |