Assay Detail
Binding
CHEMBL2167557
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Binding affinity to 5HT1A receptor by radioligand binding assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.95 | 9.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2164354 | — | — | 1 | 9.16 |
| CHEMBL2164350 | — | — | 1 | 8.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2164354 | — | Ki | = | 0.69 | nM | 9.16 |
| CHEMBL2164350 | — | Ki | = | 1.85 | nM | 8.73 |