Assay Detail
Functional
CHEMBL2168649
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anesthetic activity in Xenopus laevis tadpoles assessed as loss of of righting reflexes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Xenopus laevis |
| Tissue | Tadpole |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Allyl m-trifluoromethyldiazirine mephobarbital: an unusually potent enantioselective and photoreactive barbiturate general anesthetic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.68 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2163548 | — | — | 1 | 5.43 |
| CHEMBL2163549 | — | — | 1 | 4.42 |
| CHEMBL448 | PENTOBARBITAL | 4.0 | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2163548 | — | EC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL2163549 | — | EC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL448 | PENTOBARBITAL | EC50 | = | 65000.0 | nM | 4.19 |