Assay Detail
Functional
CHEMBL2169252
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Anesthetic activity in Xenopus laevis tadpoles assessed as loss of righting reflexes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Xenopus laevis |
| Tissue | Tadpole |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
p-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.58 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL526 | PROPOFOL | 4.0 | 1 | 5.66 |
| CHEMBL2165414 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL526 | PROPOFOL | EC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL2165414 | — | EC50 | = | 3200.0 | nM | 5.50 |