Assay Detail
Binding
CHEMBL2173398
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SYK in peripheral blood monocytes assessed as reduction FcgammaR-mediated superoxide production
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery and development of spleen tyrosine kinase (SYK) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.92 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1190711 | — | — | 1 | 7.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1190711 | — | EC50 | = | 12.0 | nM | 7.92 |