Assay Detail
Functional
CHEMBL2174701
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against doxorubicin-resistant human NCI-ADR-RES.cells incubated for 24 hrs measured after 5 days in presence of 0.2 U human plasmin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI/ADR-RES |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological characterization of protease-activated prodrugs of doxazolidine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.93 | 7.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2172463 | — | — | 1 | 7.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2172463 | — | IC50 | = | 11.75 | nM | 7.93 |