Assay Detail
Binding
CHEMBL2183448
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Staphylococcus aureus FtsZ G196A mutant expressed in Escherichia coli BL21 (DE3) at 25 degC by fluorescence anisotropy assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2180486 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2180486 | — | Kd | = | 5000.0 | nM | 5.30 |