Assay Detail
Binding
CHEMBL2184410
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Binding affinity to ETA receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Chemokine receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.29 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24461 | — | — | 1 | 8.85 |
| CHEMBL539423 | SPARSENTAN | 4.0 | 1 | 8.03 |
| CHEMBL1513 | IRBESARTAN | 4.0 | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24461 | — | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL539423 | SPARSENTAN | Ki | = | 9.3 | nM | 8.03 |
| CHEMBL1513 | IRBESARTAN | Ki | = | 10000.0 | nM | 5.00 |