Assay Detail
Binding
CHEMBL2185129
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of pig APN using L-leucine-p-nitroanilide as substrate by spectrophotometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Rapid and efficient synthesis of a novel series of substituted aminobenzosuberone derivatives as potent, selective, non-peptidic neutral aminopeptidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.17 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2179979 | — | — | 1 | 7.22 |
| CHEMBL2179978 | — | — | 1 | 7.22 |
| CHEMBL2179977 | — | — | 1 | 7.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2179979 | — | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL2179978 | — | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL2179977 | — | Ki | = | 83.0 | nM | 7.08 |