Assay Detail
Binding
CHEMBL2187142
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Escherichia coli FtsZ at 25 degC by fluorescence anisotropy assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.42 | 5.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2180486 | — | — | 1 | 5.42 |
| CHEMBL2177138 | — | — | 1 | - |
| CHEMBL2180485 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2180486 | — | Kd | = | 3800.0 | nM | 5.42 |
| CHEMBL2177138 | — | Kd | - | — | - | |
| CHEMBL2180485 | — | Kd | - | — | - |