Assay Detail

CHEMBL2187185

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Functional

Antiviral activity against Human immunodeficiency virus 1 clinical isolate

ChEMBL ↗

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Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

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Primary target Human immunodeficiency virus 1

CHEMBL378

Anchored from Assay target.

Protein identity Human immunodeficiency virus 1

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Human immunodeficiency virus 1
Confidence	1 — Organism
Curated By	Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

Type	ORGANISM
Organism	Human immunodeficiency virus 1

Publication

Chemokine receptor antagonists.

Pease J, Horuk R.
J Med Chem (2012) 55 : 9363 -9392
PubMed 22931505 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	10.21	10.21

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2110727	CENICRIVIROC	3.0	1	10.21

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2110727	CENICRIVIROC	EC50	=	0.061	nM	10.21