Assay Detail
Binding
CHEMBL2188699
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human complement factor D after 1 hr
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Factor D Inhibitors for the Treatment of AMD: Patent Highlight.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.71 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2180765 | — | — | 1 | 9.00 |
| CHEMBL2180764 | — | — | 1 | 8.70 |
| CHEMBL2180766 | — | — | 1 | 8.52 |
| CHEMBL2181048 | — | — | 1 | 4.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2180765 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL2180764 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL2180766 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL2181048 | — | IC50 | = | 24750.0 | nM | 4.61 |