Assay Detail
Binding
CHEMBL2208630
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human EGFR kinase activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synopsis of some recent tactical application of bioisosteres in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.94 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29197 | — | — | 1 | 7.16 |
| CHEMBL111038 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29197 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL111038 | — | IC50 | = | 190.0 | nM | 6.72 |