Assay Detail
Functional
CHEMBL2208708
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against respiratory syncytial virus
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Respiratory syncytial virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Respiratory syncytial virus (CHEMBL612679) ↗| Type | ORGANISM |
| Organism | Respiratory syncytial virus |
Publication
Synopsis of some recent tactical application of bioisosteres in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 7.78 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL234027 | — | — | 1 | 8.52 |
| CHEMBL233892 | — | — | 1 | 8.52 |
| CHEMBL233786 | — | — | 1 | 8.52 |
| CHEMBL446708 | — | — | 1 | 8.40 |
| CHEMBL14710 | — | — | 1 | 8.30 |
| CHEMBL388039 | — | — | 1 | 8.00 |
| CHEMBL233893 | — | — | 1 | 7.80 |
| CHEMBL392781 | — | — | 1 | 6.70 |
| CHEMBL2203633 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL234027 | — | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL233892 | — | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL233786 | — | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL446708 | — | EC50 | = | 4.0 | nM | 8.40 |
| CHEMBL14710 | — | EC50 | = | 5.0 | nM | 8.30 |
| CHEMBL388039 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL233893 | — | EC50 | = | 16.0 | nM | 7.80 |
| CHEMBL392781 | — | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL2203633 | — | EC50 | = | 5700.0 | nM | 5.24 |