Compound Detail
CHEMBL392781
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Basic Information
| ChEMBL ID | CHEMBL392781 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UCXRGCJHPVYNAL-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
372.4
MW (Da)
3.39
ALogP
7
HBA
0
HBD
81.4
PSA (Ų)
0.49
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Respiratory syncytial virus CHEMBL612679 | EC50 | 6.7 | 6.7 | 200.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Respiratory syncytial virus | EC50 | = | 202.0 | nM | 6.7 | Antiviral activity against RSV Long in HEp2 cells assessed as reduction of virus... | 17169560 |
| Respiratory syncytial virus | EC50 | = | 200.0 | nM | 6.7 | Antiviral activity against respiratory syncytial virus | 21413808 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17169560 | 10.1016/j.bmcl.2006.11.063 | ADMET | 1 |
| 17169560 | 10.1016/j.bmcl.2006.11.063 | Respiratory syncytial virus | 1 |
| 21413808 | 10.1021/jm1013693 | Respiratory syncytial virus | 1 |
Data from ChEMBL 36 via Core Engine