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Assay Detail

CHEMBL2209569

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as nitric oxide free radical scavenging activity by UV-visible spectroscopy
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Phenolic compounds from Caesalpinia sappan heartwood and their anti-inflammatory activity.
Cuong TD, Hung TM, Kim JC, Kim EH, Woo MH, Choi JS, Lee JH, Min BS.
J Nat Prod (2012) 75 : 2069 -2075
PubMed 23234407 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 13 4.36 6.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL196 ASCORBIC ACID 4.0 1 6.15
CHEMBL1916186 1 4.18
CHEMBL2043330 1 4.07
CHEMBL2208385 CAESALPINIAPHENOL C 1 4.06
CHEMBL250414 1 4.02
CHEMBL2208388 CAESALPINIAPHENOL B 1 4.02
CHEMBL249002 SAPPANONE A 1 4.01
CHEMBL1916188 1 -
CHEMBL2208384 1 -
CHEMBL2208387 1 -
CHEMBL164861 1 -
CHEMBL2208386 CAESALPINIAPHENOL D 1 -
CHEMBL2208389 CAESALPINIAPHENOL A 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL196 ASCORBIC ACID IC50 = 710.0 nM 6.15
CHEMBL1916186 IC50 = 65340.0 nM 4.18
CHEMBL2043330 IC50 = 85340.0 nM 4.07
CHEMBL2208385 CAESALPINIAPHENOL C IC50 = 86250.0 nM 4.06
CHEMBL250414 IC50 = 95450.0 nM 4.02
CHEMBL2208388 CAESALPINIAPHENOL B IC50 = 95620.0 nM 4.02
CHEMBL249002 SAPPANONE A IC50 = 96580.0 nM 4.01
CHEMBL1916188 IC50 = 116820.0 nM -
CHEMBL2208384 IC50 = 156540.0 nM -
CHEMBL2208387 IC50 = 114560.0 nM -
CHEMBL164861 IC50 = 102950.0 nM -
CHEMBL2208386 CAESALPINIAPHENOL D IC50 = 112520.0 nM -
CHEMBL2208389 CAESALPINIAPHENOL A IC50 = 102560.0 nM -