Compound Detail
CHEMBL2208386
CAESALPINIAPHENOL D Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL2208386 |
| Name | CAESALPINIAPHENOL D |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MHBAYVIIZSKIQY-AWEZNQCLSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
276.2
MW (Da)
1.69
ALogP
6
HBA
4
HBD
107.2
PSA (Ų)
0.38
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 4.91 | 4.91 | 12200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 12200.0 | nM | 4.91 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-... | 23234407 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23234407 | 10.1021/np3003673 | RAW264.7 | 6 |
| 23234407 | 10.1021/np3003673 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine