Assay Detail
Functional
CHEMBL2210778
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of growth in TSC2-deficient MEF cells after 6 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | MEF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Natural product-derived antitumor compound phenethyl isothiocyanate inhibits mTORC1 activity via TSC2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.10 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL151649 | PHENETHYLISOTHIOCYANATE | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL151649 | PHENETHYLISOTHIOCYANATE | IC50 | = | 8000.0 | nM | 5.10 |