Assay Detail
Binding
CHEMBL2212281
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX1 in BMMC cells assessed as PGD2 generation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | BMMC |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Analogue-based design, synthesis and docking of non-steroidal anti-inflammatory agents. Part 2: methyl sulfanyl/methyl sulfonyl substituted 2,3-diaryl-2,3-dihydro-1H-quinazolin-4-ones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.06 | 5.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL85139 | RUTAECARPINE | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL85139 | RUTAECARPINE | IC50 | = | 8700.0 | nM | 5.06 |