Assay Detail
Functional
CHEMBL2213248
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 Ba-L harboring reverse transcriptase V106A mutant
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Synthesis, evaluation and structure-activity relationships of triazine dimers as novel antiviral agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.26 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL70663 | DAPIVIRINE | 3.0 | 1 | 8.60 |
| CHEMBL2203851 | — | — | 1 | 6.02 |
| CHEMBL2207902 | — | — | 1 | 5.89 |
| CHEMBL2207887 | — | — | 1 | 5.73 |
| CHEMBL2207886 | — | — | 1 | 5.70 |
| CHEMBL2207917 | — | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL70663 | DAPIVIRINE | EC50 | = | 2.5 | nM | 8.60 |
| CHEMBL2203851 | — | EC50 | = | 950.0 | nM | 6.02 |
| CHEMBL2207902 | — | EC50 | = | 1290.0 | nM | 5.89 |
| CHEMBL2207887 | — | EC50 | = | 1880.0 | nM | 5.73 |
| CHEMBL2207886 | — | EC50 | = | 2010.0 | nM | 5.70 |
| CHEMBL2207917 | — | EC50 | = | 2500.0 | nM | 5.60 |