Assay Detail
Functional
CHEMBL2214289
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Vesicular stomatitis virus infected in HEL cells assessed as inhibition of virus-induced cytopathic effect
15
Total Activities
15
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vesicular stomatitis virus |
| Cell Type | HEL |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Vesicular stomatitis virus (CHEMBL613739) ↗| Type | ORGANISM |
| Organism | Vesicular stomatitis virus |
Publication
Synthesis of isoindole and benzoisoindole derivatives of teicoplanin pseudoaglycon with remarkable antibacterial and antiviral activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 15 | 4.29 | 4.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2207652 | — | — | 1 | 4.32 |
| CHEMBL2207653 | — | — | 1 | 4.28 |
| CHEMBL2207651 | — | — | 1 | 4.28 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | - |
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | - |
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | - |
| CHEMBL31634 | BRIVUDINE | 2.0 | 1 | - |
| CHEMBL2203331 | — | — | 1 | - |
| CHEMBL2207650 | — | — | 1 | - |
| CHEMBL2207649 | — | — | 1 | - |
| CHEMBL2207648 | — | — | 1 | - |
| CHEMBL2207647 | — | — | 1 | - |
| CHEMBL2207646 | — | — | 1 | - |
| CHEMBL2207645 | — | — | 1 | - |
| CHEMBL2207644 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2207652 | — | EC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL2207653 | — | EC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL2207651 | — | EC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL182 | GANCICLOVIR | EC50 | > | 100000.0 | nM | - |
| CHEMBL184 | ACYCLOVIR | EC50 | > | 250000.0 | nM | - |
| CHEMBL5314375 | CIDOFOVIR | EC50 | > | 250000.0 | nM | - |
| CHEMBL31634 | BRIVUDINE | EC50 | > | 250000.0 | nM | - |
| CHEMBL2203331 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2207650 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2207649 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2207648 | — | EC50 | > | 20000.0 | nM | - |
| CHEMBL2207647 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2207646 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2207645 | — | EC50 | > | 20000.0 | nM | - |
| CHEMBL2207644 | — | EC50 | > | 100000.0 | nM | - |