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Assay Detail

CHEMBL2215715

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Binding
Inhibition of candida albicans SAP2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Candida albicans
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Secreted aspartic protease 2 (CHEMBL6021)
Type SINGLE PROTEIN
Organism Candida albicans

Publication

Bicyclic peptidomimetics targeting secreted aspartic protease 2 (SAP2) from Candida albicans reveal a constrained inhibitory chemotype.
Calugi C, Trabocchi A, De Bernardis F, Arancia S, Navarra P, Cauda R, Cassone A, Guarna A.
Bioorg Med Chem (2012) 20 : 7206 -7213
PubMed 23123016 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.92 7.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2206678 1 7.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2206678 Ki = 12.0 nM 7.92