Assay Detail
Binding
CHEMBL2216971
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of carnitine palmitoyltransferase in rat liver mitochondria assessed as formation of formation of palmitoyl[3H]carnitine from palmitoyl-CoA and [3H]carnitine
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Subcellular | Mitochondria |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.17 | 7.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12261 | METHYL PALMOXIRATE | -1.0 | 1 | 7.34 |
| CHEMBL2216797 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12261 | METHYL PALMOXIRATE | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL2216797 | — | IC50 | = | 10000.0 | nM | 5.00 |