Assay Detail
Binding
CHEMBL2217017
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CPT2 in 24 hrs fasted rat liver mitochondria assessed as palmitoylcarnitine oxidation by radiometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Subcellular | Mitochondria |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Carnitine O-palmitoyltransferase 2, mitochondrial (CHEMBL4037) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.10 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2114397 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2114397 | — | IC50 | = | 800.0 | nM | 6.10 |