Assay Detail
Binding
CHEMBL2217160
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Inhibition of carnitine palmitoyltransferase in rat muscle using [14C]carnitine by radiometric assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Muscle tissue |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.48 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2216790 | — | — | 1 | 8.00 |
| CHEMBL2216796 | — | — | 1 | 8.00 |
| CHEMBL2216792 | — | — | 1 | 7.60 |
| CHEMBL2216797 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2216790 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL2216796 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL2216792 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL2216797 | — | IC50 | = | 500.0 | nM | 6.30 |